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AimsImprovement collaboratives consisting of various components are used throughout health care to improve quality, but no study has identified which components work best. This study tested the effectiveness of different components in addiction treatment services, hypothesizing that a combination of all components would be most effective.
DesignAn unblinded cluster‐randomized trial assigned clinics...
AimsTo examine whether tamper‐resistant formulations (TRFs) of tapentadol hydrochloride extended‐release (ER) 50 mg (TAP50) and tapentadol hydrochloride 250 mg (TAP250) could be converted into forms amenable to intranasal (study 1) or intravenous abuse (study 2).
DesignRandomized, repeated‐measures study designs were employed. A non‐TRF of OxyContin® 40 mg (OXY40) served as a positive control. No...
AimTo evaluate whether venlafaxine‐extended release (VEN‐XR) is an effective treatment for cannabis dependence with concurrent depressive disorders.
DesignThis was a randomized, 12‐week, double‐blind, placebo‐controlled trial of out‐patients (n = 103) with DSM‐IV cannabis dependence and major depressive disorder or dysthymia. Participants received up to 375 mg VEN‐XR on a fixed‐flexible schedule...
Smoking cue‐exposure research has provided a powerful tool for examining cravings in the laboratory. A key attraction of this method is that tightly controlled experimental procedures can model craving experiences that are presumed to relate to addiction. Despite its appeal, key assumptions underlying the clinical relevance of smoking cue‐reactivity studies have been questioned recently. For both...
AimsTo estimate age‐period‐cohort models predicting alcohol volume, heavy drinking and beverage‐specific alcohol volume in order to evaluate whether the 1976–1985 birth cohorts drink relatively heavily.
DesignData from seven cross‐sectional surveys of the USA conducted between 1979 and 2010 were utilized in negative binomial generalized linear models of age, period and cohort effects predicting alcohol...
Aims The aim of this paper is to offer an account of the history and current status of gambling research in the United States.
Methods A review of the literature.
Results Gambling has been a part of society in the United States since its early history. However, it was not until 1980 that the medical profession in the United States first recognized pathological gambling as a psychiatric disorder...
In [1], the following error was published on p. 550, Table :There were errors in the percentages reported in the suicide column.The corrected table is reproduced below (with corrected numbers in grey):The text on page 549 should read:Table displays drug presence among suicide and homicide decedents. Alcohol was identified in 42.2% of all tested cases and was more common among homicide (48.9%) than...
AimTo investigate relationships between periodic increases in minimum alcohol prices, changing densities of liquor stores and alcohol‐attributable (AA) deaths in British Columbia, Canada.
DesignCross‐section (16 geographic areas) versus time–series (32 annual quarters) panel analyses were conducted with AA deaths as dependent variables and price, outlet densities and socio‐demographic characteristics...
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